Jun 1, 2021 12:37
3 yrs ago
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English term

Abnormal activation of BTK-related signaling pathways

English to Russian Medical Medical: Pharmaceuticals
Bruton’s Tyrosine Kinase (BTK) is a member of the TEC family of non-receptor tyrosine kinases and is expressed in B lymphocytes, mast cells, macrophages, monocytes, and neutrophils. It is a key kinase in the B cell receptor (BCR) signaling pathway and regulates B cell proliferation, survival, differentiation, and cytokine expression. Abnormal activation of BTK-related signaling pathways can lead to autoimmune diseases and is closely related to the occurrence and development of B cell malignancies (Kil et al., 2012).
Change log

Jun 1, 2021 12:37: changed "Kudoz queue" from "In queue" to "Public"

Proposed translations

+1
3 mins
Selected

патологическая активация сигнальным путей, связанных с BTK

То есть сигнальных путей, опосредуемых BTK.
Peer comment(s):

agree Natalie : Я бы вместо "патологическая" написала "аномальная"
13 mins
Спасибо, Наталья!
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4 KudoZ points awarded for this answer. Comment: "Спасибо"
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