Nov 11, 2020 17:52
3 yrs ago
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English term

missing equals failure analysis

English to Russian Medical Medical: Pharmaceuticals исследование
Secondary efficacy endpoints were the proportion of patients with HBV DNA less than 20 IU/mL, by missing equals failure analysis, the proportions of patients with HBeAg loss and seroconversion to anti-HBe, and the proportion of patients with HBsAg loss and seroconversion to anti-HBs. Как точнее сформулировать
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анализ, при котором отсутствие данных эквивалентно (считается) безуспешному лечению

http://tb-hiv.ru/doc_pdf/vih_and_tuber/aids-2_2009.pdf
При использовании критерия «отсутствие данных эквивалентно безуспешному лечению» (ITTM = F — intention-to-treat
missing equals failure) лечение считается успешным при
условии регистрации у пациента неопределяемой вирусной нагрузки ВИЧ на момент окончания исследования;

https://www.tandfonline.com/doi/abs/10.1080/1054340090324274...
Consider a diabetes trial where the endpoint is the successful control of HbA1c
for subjects with elevated HbA1c at baseline. In this case, the discontinuation of
treatment for any reason would imply that the subject’s HbA1c would not have
been successfully controlled if the subject had been followed off treatment. In this
case, missing equals failure is appropriate.
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