May 18, 2023 06:19
12 mos ago
36 viewers *
English term

deleted cancer

English to Russian Medical Medical (general)
SMARCA4 is frequently mutated in primary tumors (i.e., deleted or inactivated), particularly in lung cancer (12%), melanoma, liver cancer and pancreatic cancer.

SMARCA2 is one of the top essential genes in SMARCA4-mutant (deleted) cancer cell line.

Сancer is SMARCA4 deleted cancer
Proposed translations (Russian)
3 см.

Proposed translations

4 days
Selected

см.

Рак представляет собой рак, полученный/развившийся в результате делеции гена SMARCA4.
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4 KudoZ points awarded for this answer.

Reference comments

1 day 8 hrs
Reference:

different parsing

https://preludetx.com › uploads › 2021/04 › S...
PDF
****deletion of SMARCA4-mutant cancer cell line****. from preludetx.com
nonsense, frameshift deletion, splice site mutations) and SMARCA4-deleted cancer cells are highly dependent on its paralog gene SMARCA2 for their survival.

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Note added at 1 jour 8 heures (2023-05-19 14:53:19 GMT)
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https://meridian.allenpress.com › aplm › article › SMAR...
9 Apr 2020 — The ****SMARCA4 mutations/deletions****, best investigated in NSCLC cell lines, predominantly involve the bromodomain, resulting in a truncated BRG1 ...

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Note added at 1 jour 8 heures (2023-05-19 14:57:38 GMT)
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https://www.proz.com/personal-glossaries/entry/35213285-gene...
Peer comments on this reference comment:

agree Igor Andreev
2 days 19 hrs
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