Glossary entry (derived from question below)
English term or phrase:
declare failure of beta-blockade
Russian translation:
[не] считать бета-блокаду отсутствующей
Added to glossary by
Lesia Kutsenko
Feb 9, 2021 12:08
3 yrs ago
18 viewers *
English term
Russian Federation
"Золотое копьё" 2021. 13 лет опыта.
Native in: Russian 
Works in: English to Russian, Russian to English, German to Russian, and 1 more.
declare failure of beta-blockade
English to Russian
Medical
Medical: Health Care
Beta-blockers were the first studied medication for treatment of dynamic outflow tract obstruction and are generally considered the first-line agent for most patients with obstructive HCM. Medications should be titrated to a dose where there is symptom benefit but *not declare failure of beta-blockade* until there is demonstrated physiologic evidence of beta-blockade (i.e., suppression of resting heart rate).
Proposed translations
(Russian)
| 3 | [не] считать бета-блокаду отсутствующей |
Lesia Kutsenko
|
| 4 +1 | не обнаруживается неэффективность блокады бета-адренорецепторов |
Doctor Alex
|
| 3 | * |
hawkwind
|
Change log
Oct 1, 2021 21:22: Lesia Kutsenko Created KOG entry
Proposed translations
10 mins
Lesia Kutsenko
Canada
Canada
Native in English
&
Russian
Works in field
Canada
Life-saving precise translations
Native in: English (Variant: US) 
, Russian (Variant: Standard-Russia)
Works in: Russian to English, Ukrainian to English, English to Ukrainian, and 2 more.
Related KudoZ points
:
47
Selected
[не] считать бета-блокаду отсутствующей
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Note added at 1 hr (2021-02-09 13:12:19 GMT)
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Доза препарата должна быть минимальной, при которой облегчаются симптомы, но не следует считать бета-блокаду отсутствующей до тех пор, пока не будут выявлены ее физиологические свидетельства (т.е. подавление ЧСС в покое)
Note from asker:
| Спасибо за ответ, но не могу понять логику фразы и как "medications" могут "declare". А если считать, что перед "not" пропущено "do", тогда неясно, как логически увязать это с частью фразы после "until". |
4 KudoZ points awarded for this answer.
Comment: "Простите, забыл про этот вопрос. Большое спасибо за помощь."
+1
2 hrs
Doctor Alex
Native in Russian
Specializes in field
Medical translation by medical doctor
Native in: Russian , Ukrainian
Works in: English to Russian
Related KudoZ points
:
76
не обнаруживается неэффективность блокады бета-адренорецепторов
или "не обнаруживается недостаточная блокада бета-адренорецепторов"
1 day 20 hrs
*
увеличивать дозу до улучшения целевой симптоматики, но без возникновения побочных эффектов, которые потребуют отмены терапии (т. е. укажут на неудачный выбор дозировки терапии бета-блокаторами)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481297/
Beta blockers should be initiated at low doses and titrated slowly to target doses if tolerable (Table 1). Adverse events include fluid retention and worsening HFrEF, fatigue, bradycardia or heart block, and hypotension. The fluid retention or worsening HFrEF associated with beta blockers do not generally warrant the permanent withdrawal of treatment. Beta-blocker-induced bradycardia is generally asymptomatic and thus requires no treatment; however, if the bradycardia is accompanied by dizziness, lightheadedness, or second- or third-degree heart block, the dose of the beta blocker should be decreased.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481297/
Beta blockers should be initiated at low doses and titrated slowly to target doses if tolerable (Table 1). Adverse events include fluid retention and worsening HFrEF, fatigue, bradycardia or heart block, and hypotension. The fluid retention or worsening HFrEF associated with beta blockers do not generally warrant the permanent withdrawal of treatment. Beta-blocker-induced bradycardia is generally asymptomatic and thus requires no treatment; however, if the bradycardia is accompanied by dizziness, lightheadedness, or second- or third-degree heart block, the dose of the beta blocker should be decreased.
Discussion